Home/ Questions/Q 3179
Next
In Process
Anonymous
  • 0
Asked: 2020-08-19T22:41:03+00:00 In:

How does excessive use of loop diuretics cause or precipitate hepatic encephalopathy in a person with a pre-existing liver disease?

  • 0

How does excessive use of loop diuretics cause or precipitate hepatic encephalopathy in a person with a pre-existing liver disease?

diureticsencephalopathyliverliver impairmentloop diuretics
Share

    Related Questions

    Leave an answer

    You must login to add an answer.

    Need An Account,

    1 Answer

    1. ehoneahobed Eminent Member I am the Africapreneur. Finding solutions to African-based problems through software development is my dream

      Hepatic encephalopathy is usually as a result of the accumulation of nitrogenous waste especially ammonia in the central nervous system. This happens commonly because of the inability of the liver to detoxify ammonia and other chemicals. The use of loop diuretics is known to cause a decrease in potaRead more

      Hepatic encephalopathy is usually as a result of the accumulation of nitrogenous waste especially ammonia in the central nervous system. This happens commonly because of the inability of the liver to detoxify ammonia and other chemicals.

      The use of loop diuretics is known to cause a decrease in potassium levels and also lead to alkalosis which facilitates the conversion of ammonium (NH4+) to ammonia (NH3). The excessive production of ammonia then causes accumulation in the CNS leading to the encephalopathy.

      Also, diuretic-induced hypovolemia is the most common reason for patients with previously well-controlled hepatic encephalopathy to present to the emergency room with worsening mental function.

      See less
      • 0